منابع مشابه
Regulation of miR‐200c and miR‐141 by Methylation in Prostate Cancer
BACKGROUND In prostate cancer (PCa), abnormal expression of several microRNAs (miRNAs) has been previously reported. Increasing evidence shows that aberrant epigenetic regulation of miRNAs is a contributing factor to their altered expression in cancer. In this study, we investigate whether expression of miR-200c and miR-141 in PCa is related to the DNA methylation status of their promoter. ME...
متن کاملEvaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
Bladder cancer (BC) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. MiRNAs expression has noticeable role in bladder tumorigenesis. The purpose of this study was to assess miR-200c, miR-30b and miR-141 in tissue samples of patients with BC and healthy adjacent tissue samples and their association with muscle invasion, grade...
متن کاملRole for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells
BACKGROUND The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/P...
متن کاملevaluation of mir-141, mir-200c, mir-30b expression and clinicopathological features of bladder cancer
bladder cancer (bc) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. mirnas expression has noticeable role in bladder tumorigenesis. the purpose of this study was to assess mir-200c, mir-30b and mir-141 in tissue samples of patients with bc and healthy adjacent tissue samples and their association with muscle invasion, grade...
متن کاملEvaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
Bladder cancer (BC) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. MiRNAs expression has noticeable role in bladder tumorigenesis. The purpose of this study was to assess miR-200c, miR-30b and miR-141 in tissue samples of patients with BC and healthy adjacent tissue samples and their association with muscle invasion, grade...
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ژورنال
عنوان ژورنال: The Prostate
سال: 2016
ISSN: 0270-4137
DOI: 10.1002/pros.23201